RNA

Part:BBa_K2923008:Design

Designed by: claire husser   Group: iGEM19_Strasbourg   (2019-09-13)

Guanine inactif aptazyme


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Aptazyme is composed of three different parts: Gua_eco1 as a communication module, a ribozyme module with inactivating A→G mutation and aptamer module specific to guanine.



Source

Stifel, J., Spöring, M., and Hartig, J.S. (2019). Expanding the toolbox of synthetic riboswitches with guanine-dependent aptazymes. Synthetic Biology 4.