RNA
Part:BBa_K2923008:Design
Designed by: claire husser Group: iGEM19_Strasbourg (2019-09-13)
Guanine inactif aptazyme
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Aptazyme is composed of three different parts: Gua_eco1 as a communication module, a ribozyme module with inactivating A→G mutation and aptamer module specific to guanine.
Source
Stifel, J., Spöring, M., and Hartig, J.S. (2019). Expanding the toolbox of synthetic riboswitches with guanine-dependent aptazymes. Synthetic Biology 4.